Confirm delete?

Bertin Bioreagent
logo
All categories
Contact Us
You are here :

Docosahexaenoyl Ethanolamide-d4

  • Zoom
    Docosa<wbr/>hexaenoyl Ethanolamide-<wbr/>d<sub>4</sub>
  • Docosa<wbr/>hexaenoyl Ethanolamide-<wbr/>d<sub>4</sub>
Cat No: 9001108
Biochemicals - Isotopically Labeled Standards
Cayman

Docosahexaenoyl ethanolamide-d4 contains four deuterium atoms at the 1, 1', 2, and 2' positions. It is intended for use as an internal standard for the quantification of docosahexaenoyl ethanolamide by GC- or LC-mass spectrometry (MS). Docosahexaenoic...

More

This product can only be bought through Cayman Chemical. Please contact us.

Territorial Availability: Available through Bertin Technologies only in France
Synonyms:
  • N-(2-hydroxyethyl-1,1',2,2'-d4)-4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenamide
Correlated keywords:
  • neurochemistry neuroscience endocannabinoids brain retina docosahexaenoic acids DHA fatty w-3 .omega.-3 neural tissues ethanolamines ethanolamides arachidonoyl AEA lipids extracts piglets diets rats CB1 receptors shaker-related voltage-gated potassium channels cannabinoids cbs synthetic DEA deuterateds deuteriums LC-MS GC/MS GC-MS mass spectrometry LC/MS MS
Product Overview:
Docosahexaenoyl ethanolamide-d4 contains four deuterium atoms at the 1, 1', 2, and 2' positions. It is intended for use as an internal standard for the quantification of docosahexaenoyl ethanolamide by GC- or LC-mass spectrometry (MS). Docosahexaenoic Acid (DHA) is an essential fatty acid and the most abundant ω-3 fatty acid in neural tissues, especially in the retina and brain. Docosahexaenoyl ethanolamide (DHEA) is the ethanolamine amide of DHA that has been detected in both brain and retina at concentrations similar to those for arachidonoyl ethanolamide (AEA).{3424,10520} A 9.5 fold increase of DHEA was observed in brain lipid extracts from piglets fed a diet supplemented with DHA compared to a control diet without DHA.{13860} DHEA binds to the rat brain CB1 receptor with a Ki value of 324 nM, which is approximately 10-fold higher than the Ki value for AEA.{9580} DHEA inhibits shaker-related voltage-gated potassium channels in brain slightly better than AEA, with an IC50 value of 1.5 µM.{13859}
Size 100 µg
Shipping dry ice
CAS Number 946524-43-2
Molecular Formula C24H33D4NO2
SMILES O=C(NC([2H])([2H])C([2H])([2H])O)CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CC
Molecular Weight 375,6
Formulation A solution in ethanol
Purity ≥99% deuterated forms (d1-d4)
Custom Code 3822.19
UNSPSC code 12352100

Click here to ask for your quote and get 15% off Cayman's products.

 

Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.

/ We also advise you

Cross selling for this product : Docosa<wbr/>hexaenoyl Ethanolamide-<wbr/>d<sub>4</sub> There are 3 products.

Search