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3,3',5-Triiodo-L-thyronine (sodium salt hydrate)

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    3,3',5-<wbr/>Triiodo-<wbr/>L-<wbr/>thyronine (sodium salt hydrate)
  • 3,3',5-<wbr/>Triiodo-<wbr/>L-<wbr/>thyronine (sodium salt hydrate)
Cat No: 16028
Biochemicals - Receptor Pharmacology
Cayman

3,3',5-Triiodo-L-thyronine (T3) is a thyroid hormone.{61095} It is produced by 5'-monodeiodination of the prohormone thyroxine (T4) in various tissues, including liver and kidney. T3 is an agonist of thyroid hormone receptors TRα and TRβ (Kis = 2.3 nM...

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This product can only be bought through Cayman Chemical. Please contact us.

Territorial Availability: Available through Bertin Technologies only in France
Synonyms:
  • O-(4-hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine, monosodium salt, hydrate
Correlated keywords:
  • 6893-02-3 7013-53-8 57164-27-9 Basoprocin Cynomel Cytobin Cytomel Ibiothyron Liothyronine Tertroxin Triostat Triothyrone mono deiodination T 4 3 TR ? ? HEK 293 LAT 1 55-06-1
Product Overview:
3,3',5-Triiodo-L-thyronine (T3) is a thyroid hormone.{61095} It is produced by 5'-monodeiodination of the prohormone thyroxine (T4) in various tissues, including liver and kidney. T3 is an agonist of thyroid hormone receptors TRα and TRβ (Kis = 2.3 nM for both) that modulates diverse biological properties, including metabolism, cardiac function, growth, and redox signaling.{27008,27007,27010,27009} It also functions as an inhibitor of L-type amino acid transporter 1 (LAT1), inhibiting LAT1-mediated leucine uptake in HEK293 cells when used at a concentration of 10 µM.{59277}
Size 100 mg
Shipping dry ice
CAS Number 345957-19-9
Molecular Formula C15H11I3NO4 • Na [XH2O]
SMILES IC1=C(OC2=CC(I)=C(O)C=C2)C(I)=CC(C[C@@H](C([O-])=O)N)=C1.[Na+].O
Molecular Weight 673
Formulation A crystalline solid
Purity ≥98%
Custom Code 2903.99
UNSPSC code 12352100

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Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

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