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(±)12(13)-EpOME-d4

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    (±)12(13)-<wbr/>EpOME-d<sub>4</sub>
  • (±)12(13)-<wbr/>EpOME-d<sub>4</sub>
Cat No: 10009996
Biochemicals - Isotopically Labeled Standards
Cayman

(±)12(13)-EpOME-d4 is intended for use as an internal standard for the quantification of 12(13)-EpOME by GC- or LC-MS. 12(13)-EpOME is an epoxide formed primarily via metabolism of linoleic acid (Item Nos. 90150
90150.1
21909) by the cytochrome P4...

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This product can only be bought through Cayman Chemical. Please contact us.

Territorial Availability: Available through Bertin Technologies only in France
Synonyms:
  • (±)12(13)epoxy-9Z-octadecenoic-9,10,12,13-d4 acid
Correlated keywords:
  • deuterated deuterium GCMS LCMS P 450 2J2 2C8 2C9 1A1 Iso leukotoxin Isoleuko toxin
Product Overview:
(±)12(13)-EpOME-d4 is intended for use as an internal standard for the quantification of 12(13)-EpOME by GC- or LC-MS. 12(13)-EpOME is an epoxide formed primarily via metabolism of linoleic acid (Item Nos. 90150
90150.1
21909) by the cytochrome P450 (CYP) isoforms CYP2J2, CYP2C8, and CYP2C9, however, CYP1A1 can contribute to 12(13)-EpOME production when pharmacologically induced.{59199} 12(S),13(R)-EpOME and 12(R),13(S)-EpOME are produced at equal proportions from linoleic acid by peroxygenase, whereas CYP450-mediated metabolism of linoleic acid exclusively produces 12(S),13(R)-EpOME, in E. lagascae microsomes.{58450}
Size 25 µg
Shipping dry ice
Molecular Formula C18H28D4O3
SMILES CCCCC[C@]1([2H])[C@](O1)([2H])C/C([2H])=C([2H])\CCCCCCCC(O)=O
Molecular Weight 300,5
Formulation A solution in methyl acetate
Purity ≥99% deuterated forms (d1-d4)
Custom Code 3822.00
UNSPSC code 12352100

Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.

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