5(S),6(R)-11-trans DiHETE

Biochemicals - Lipids

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Cat No: 10009628

Biochemicals - Lipids

5(S),6(R)-11-trans DiHETE is a C-11 double bond isomer of 5(S),6(R)-DiHETE that is formed by the enzymatic isomerization of 5(S),6(R)-DiHETE by a membrane bound factor.{14924} 5(S),6(R)-11-trans DiHETE has been found in rat kidney homogenates and is p...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

11-trans-5S,6R-dihydroxy-7E,9E,11E,14Z-eicosatetraenoic acid

Correlated keywords:

5(S),6(S)-diHETE LTA4 LTB4 6-trans-12-epi epoxides hydrolase kidneys rats homogenates

Product Overview:
5(S),6(R)-11-trans DiHETE is a C-11 double bond isomer of 5(S),6(R)-DiHETE that is formed by the enzymatic isomerization of 5(S),6(R)-DiHETE by a membrane bound factor.{14924} 5(S),6(R)-11-trans DiHETE has been found in rat kidney homogenates and is potentially formed by the epoxide hydrolase pathway in this tissue.{14924} The isomerase activity responsible for the conversion of leukotriene B4 (LTB4) to 6-trans LTB4 in rat kidney homogenates has also been implicated in its formation.{14925} 5(S),6(R)-11-trans DiHETE is not a substrate for soybean lipoxygenase.{14924} The biological activity of 5(S),6(R)-11-trans DiHETE has not been reported.

Size	25 µg
Shipping	dry ice
CAS Number	129263-59-8
Molecular Formula	C₂₀H₃₂O₄
SMILES	CCCCC/C=C\C/C=C/C=C/C=C/[C@@H](O)[C@@H](O)CCCC(O)=O
Molecular Weight	336,5
Formulation	A solution in ethanol
Purity	≥95%
Custom Code	2916.19
UNSPSC code	12352100

Technical File

MSDS

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

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ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.

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