Leukotriene B4 Express ELISA Kit

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Leukotriene B₄ Express ELISA Kit

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Cat No: 10009292

Assay Kits - Elisa

LTB4 stimulates a number of leukocyte functions, including aggregation, stimulation of ion fluxes, enhancement of lysosomal enzyme release, superoxide anion production, chemotaxis, and chemokinesis. Plasma levels of LTB4 increase from 100 ng/ml follow...

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Territorial Availability: Available through Bertin Technologies only in France

Correlated keywords:

same-day leukotrienes LTB4 enzymes immunoassays ELISAs kits assays measures measurements arachidonic acids 5-lipoxygenases 5-LOs LTA4 A4 hydrolases mediators inflammatory inflammation leukocytes aggregation ion fluxes lysosomal release superoxides anions SOs chemotaxis chemokinesis human neutrophils degranulations plasmas blood serums hepatocytes 20-hydroxy 20-carboxy NADPH-dependent cytochromes P450 CYP450s b-oxidations .beta.-oxidations ?-oxidations w-carboxy dinor .omega.-carboxy ?-carboxy tetranor-LTB4 competitive quantification sample matrices

Product Overview:
LTB4 stimulates a number of leukocyte functions, including aggregation, stimulation of ion fluxes, enhancement of lysosomal enzyme release, superoxide anion production, chemotaxis, and chemokinesis. Plasma levels of LTB4 increase from 100 ng/ml following leukocyte stimulation. LTB4 is metabolized in leukocytes and hepatocytes to less active 20-hydroxy and 20-carboxy LTB4 and then further oxidized to ω-carboxy dinor LTB4 and ω-carboxy tetranor-LTB3. LTB4 is not excreted in the urine. Cayman’s LTB4 Express ELISA Kit is a competitive assay that can be used for quantification of LTB4 in plasma and other sample matrices. The assay has a range from 15.6-2,000 pg/ml and a sensitivity (80% B/B0) of approximately 45 pg/ml.

Size	96 solid wells
Shipping	dry ice
Custom Code	3822.19
UNSPSC code	41116104

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.