Suc-Leu-Tyr-AMC

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Suc-Leu-Tyr-AMC

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Cat No: 10008120

The calpains are a family of calcium-dependent cysteine proteases, with calpain I (µ-calpain) requiring micromolar calcium and calpain II (m-calpain) requiring millimolar calcium. Suc-Leu-Tyr-AMC is a fluorescent substrate for calpain I and II and papa...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

N-(3-carboxy-1-oxopropyl)-L-leucyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-tyrosinamide

Correlated keywords:

fluorescent substrate calpain papain peptidase 20S proteasome biochemical enzyme ubiquitin sucleutyramc suclyamc

Product Overview:
The calpains are a family of calcium-dependent cysteine proteases, with calpain I (µ-calpain) requiring micromolar calcium and calpain II (m-calpain) requiring millimolar calcium. Suc-Leu-Tyr-AMC is a fluorescent substrate for calpain I and II and papain (another cysteine protease) that is used for measuring the chymotrypsin-like peptidase activity of the 20S proteasome (excitation max: 360 nm; emission max: 460 nm).{29239,29240,29241} Suc-Leu-Tyr-AMC can also be cleaved by the Ti protease from E. coli.{13747}

Size	5 mg
Shipping	dry ice
CAS Number	94367-20-1
Molecular Formula	C₂₉H₃₃N₃O₈
SMILES	CC(C1=CC=C(C=C1O2)NC([C@H](CC3=CC=C(C=C3)O)NC([C@@H](NC(CCC(O)=O)=O)CC(C)C)=O)=O)=CC2=O
Molecular Weight	551,6
Formulation	A crystalline solid
Purity	≥98%
Custom Code	2922.19
UNSPSC code	12352100

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