13,14-dihydro-15-keto Prostaglan

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13,14-dihydro-15-keto Prostaglandin A₂ MaxSpec^® Standard

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Cat No: 10007200

Biochemicals - Analytical Standards

Prostaglandin E2 (PGE2; Item Nos. 14010
10007211) is metabolized rapidly to 13,14-dihydro-15-keto PGE2 (Item Nos. 14650
10007214), which is present in the plasma of humans and other mammals. 13,14-dihydro-15-keto PGA2 results from the non-enzymati...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

9,15-dioxo-prosta-5Z,10-dien-1-oic acid

Correlated keywords:

pga2 metabolite quantitative standard mass spec spectrometry lipidomics LC-MS

Product Overview:
Prostaglandin E2 (PGE2; Item Nos. 14010
10007211) is metabolized rapidly to 13,14-dihydro-15-keto PGE2 (Item Nos. 14650
10007214), which is present in the plasma of humans and other mammals. 13,14-dihydro-15-keto PGA2 results from the non-enzymatic dehydration of 13,14-dihydro-15-keto PGE2, a process which is accelerated by the presence of albumin.{581,366} Further decomposition of 13,14-dihydro-15-keto PGA2 by the intentional addition of base produces bicyclo PGE2 (Item No. 14530), a stable marker of PGE2 biosynthesis.{366} 13,14-dihydro-15-keto PGA2 MaxSpec® standard is a quantitative grade standard of 13,14-dihydro-15-keto PGA2 (Item No. 10260) that has been prepared specifically for mass spectrometry or any application where quantitative reproducibility is required. The solution has been prepared gravimetrically and is supplied in a deactivated glass ampule sealed under argon. The concentration was verified by comparison to an independently prepared calibration standard. This 13,14-dihydro-15-keto PGA2 MaxSpec® standard is guaranteed to meet identity, purity, stability, and concentration specifications and is provided with a batchspecific certificate of analysis. Ongoing stability testing is performed to ensure the concentration remains accurate throughout the shelf life of the product. Note: The amount of solution added to the vial is in excess of the listed amount. Therefore, it is necessary to accurately measure volumes for preparation of calibration standards. Follow recommended storage and handling conditions to maintain product quality.

Size	100 µg
Shipping	dry ice
CAS Number	74872-89-2
Molecular Formula	C₂₀H₃₀O₄
SMILES	CCCCCC(=O)CC[C@H]1C=CC(=O)[C@H]1C/C=C\CCCC(=O)O
Molecular Weight	334,5
Formulation	A solution in methyl acetate at 100 µg/ml
Purity	≥95%
Custom Code	3822.19
UNSPSC code	12352100

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.

13,14-dihydro-15-keto Prostaglandin A2 MaxSpec® Standard