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(±)5-iPF2?-VI-d11

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    (±)5-<wbr/>iPF<sub>2?</sub>-<wbr/>VI-<wbr/>d<sub>11</sub>
  • (±)5-<wbr/>iPF<sub>2?</sub>-<wbr/>VI-<wbr/>d<sub>11</sub>
Cat No: 10006654
Biochemicals - Isotopically Labeled Standards
Cayman

(±)5-iPF2α-VI-d11 contains 11 deuterium atoms at the 16, 16, 17, 17, 18, 18, 19, 19, 20, 20, and 20 positions. It is intended for use as an internal standard for the quantification of (±)5-iPF2α-VI (Item No. 16300) by GC- or LC-mass spectrometry. Isop...

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Territorial Availability: Available through Bertin Technologies only in France
Synonyms:
  • (±)5,9?,11?-trihydroxy-(8?)-prosta-6E,14Z-dien-1-oic-16,16,17,17,18,18,19,19,20,20,20-d11 acid
Correlated keywords:
  • isoprostanes peroxidation oxidative injury deuterateds deuteriums isotopes 8,12-isoprostanes iPF2alpha-VI-d11 prostaglandins iPF2a-VI-d11 urine peroxidative damage enantiomers stress 316300 iPF2?-VI-d4 iPF2?VId4 iPF2?VI-d4 iPF2?-VId4
Product Overview:
(±)5-iPF2α-VI-d11 contains 11 deuterium atoms at the 16, 16, 17, 17, 18, 18, 19, 19, 20, 20, and 20 positions. It is intended for use as an internal standard for the quantification of (±)5-iPF2α-VI (Item No. 16300) by GC- or LC-mass spectrometry. Isoprostanes are prostaglandin-like products of free-radical induced lipid peroxidation.{320} Although the isoprostanes derived from arachidonic acid are the best characterized, many other polyunsaturated fatty acids can form isoprostanes.{7323} iPF2α-VI is one of dozens of possible stereo- and regioisomeric isoprostanes which can be formed from arachidonic acid. To date, the most extensively studied of these is 8-isoprostane (8-epi-PGF2α, iPF2α-III).{3064,5011} However, 8-isoprostane is a minor isoprostane constituent when compared to some of the other isomers which form in natural conditions of oxidative stress,{8367} including iPF2α-VI of the type-VI isoprostanes. This class has been shown to be one of the major isoprostane products, in contrast to 8-isoprostane. In addition to being produced in greater abundance than 8-isoprostane, Type VI isoprostanes form internal lactones which facilitate their extraction and purification from biological samples.{8367,9408,6910,6390}
Size 10 µg
Shipping dry ice
CAS Number 936565-17-2
Molecular Formula C20H23D11O5
SMILES CCCCC/C=C\C[C@H]1C(O)CC(O)[C@H]1\C=C\C(O)CCCC(=O)O
Molecular Weight 365,6
Formulation A solution in ethanol
Purity ≥99% deuterated forms (d1-d11)
Custom Code 3822.19
UNSPSC code 12352100

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

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ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.

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