Estriol

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Estriol

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Cat No: 10006484

Biochemicals - Lipids

Estriol is a metabolite of estradiol and a major estrogen produced in the later stages of pregnancy. In a longitudinal study in healthy pregnant women, total plasma estriol levels increased from 10 weeks gestation to approximately 150 ng/ml at week 38...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

estra-1,3,5(10)-triene-3,16?,17?-triol

Correlated keywords:

pregnancy pregnancies steroids 17.beta.-estradiol 17b-estradiol 17beta-estradiol estrogens plasma saliva fetal dehydroepiandrosterone sulfate DHEAS adrenal glands metabolites endocrinology

Product Overview:
Estriol is a metabolite of estradiol and a major estrogen produced in the later stages of pregnancy. In a longitudinal study in healthy pregnant women, total plasma estriol levels increased from 10 weeks gestation to approximately 150 ng/ml at week 38.{7767} The majority of the estriol synthesized in the later stages of pregnancy originates from fetal dehydroepiandrosterone sulfate (DHEAS) and serves as a direct marker of fetal adrenal gland activity.{7766} Saliva contains primarily unbound and unconjugated estriol and is commonly used for monitoring estriol levels.{7766,7799} Plasma levels of estriol in males and non-pregnant females is less than 2 ng/ml.{7647}

Size	100 mg
Shipping	dry ice
CAS Number	50-27-1
Molecular Formula	C₁₈H₂₄O₃
SMILES	Oc1ccc2c(CC[C@@H]3C2CC[C@]2(C)[C@@H](O)C(O)CC32)c1
Molecular Weight	288,4
Formulation	A crystalline solid
Purity	≥95%
Custom Code	2937.23
UNSPSC code	12352100

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

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ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.