Estrone-d2

Confirm delete?

Estrone-d₂

Zoom

Cat No: 9002844

Biochemicals - Isotopically Labeled Standards

Estrone-d2 is intended for use as an internal standard for the quantification of estrone (Item Nos. ISO60165
10006485) by GC- or LC-MS. Estrone is one of the three naturally occurring estrogens, the others being estradiol (Item Nos. ISO60155
10006...

This product can only be bought through Cayman Chemical. Please contact us.

Product Overview
Data
Downloads
About Cayman

Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

3-hydroxy-estra-1,3,5(10)-trien-17-one-2,4-d2

Correlated keywords:

estrone estrogen estradiol 17?-estradiol 17b-estradiol deuterated deuterium GC-MS GC/MS gas chromatography mass spectrometry LC-MS LC/MS isotope GCMS LCMS

Product Overview:
Estrone-d2 is intended for use as an internal standard for the quantification of estrone (Item Nos. ISO60165
10006485) by GC- or LC-MS. Estrone is one of the three naturally occurring estrogens, the others being estradiol (Item Nos. ISO60155
10006315) and estriol (Item Nos. ISO60164
10006484).{9611} Estrone is synthesized from androstenedione (Item No. ISO60161) by the aromatase enzyme system in the ovaries and placenta, and is also synthesized from estradiol by 17-hydroxy steroid dehydrogenase in the liver.{9611,8343} Serum concentrations of estrone in premenopausal women fluctuate according to the menstrual cycle and becomes the most predominant estrogen in postmenopausal women.{9611} The binding affinities of estrone to the estrogen receptors α and β are approximately 60% and 37% relative to estradiol.{9611}

Size	500 µg
Shipping	dry ice
CAS Number	350820-16-5
Molecular Formula	C₁₈H₂₀D₂O₂
SMILES	O=C1CC[C@@]2([H])[C@]3([H])CCC4=C([2H])C(O)=C([2H])C=C4[C@@]3([H])CC[C@@]21C
Molecular Weight	272,4
Formulation	A crystalline solid
Purity	≥98%
Custom Code	3822.19
UNSPSC code	12352100

Technical File

MSDS

Click here to ask for your quote and get 15% off Cayman's products.

Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.