Confirm delete?

Bertin Bioreagent
logo
All categories
Contact Us
You are here :

PRE-084 (hydrochloride)

  • Zoom
    PRE-<wbr/>084 (hydro<wbr>chloride)
  • PRE-<wbr/>084 (hydro<wbr>chloride)
Cat No: 9001329
Biochemicals - Analytical Standards
Cayman

Sigma receptors are a structurally unique class of intracellular proteins that can be activated by the following agonists: cocaine, morphine/diacetylmorphine, opipramol, PCP, fluvoxamine, methamphetamine, dextromethorphan, and the herbal antidepressant...

More

This article is not for sale online.
Contact us for more information about this article.

Territorial Availability: Available through Bertin Technologies only in France
Technical Warning: Bertin Technologies restricts the sale of this product to licensed controlled substance laboratories and qualified academic research institutions. Please contact us for further details.
Special Advice: Please check regulation status before ordering; additionel fees can apply.
Synonyms:
  • 1-phenyl-2-(4-morpholinyl)ethyl ester-cyclohexanecarboxylic acid, monohydrochloride
Correlated keywords:
  • 138847-85-5 sigma receptors agonists ?1 cocaine morphine diacetylmorphine opipramol PCP fluvoxamine methamphetamine dextromethorphan antidepressant berberin hydrochloride HCl
Product Overview:
Sigma receptors are a structurally unique class of intracellular proteins that can be activated by the following agonists: cocaine, morphine/diacetylmorphine, opipramol, PCP, fluvoxamine, methamphetamine, dextromethorphan, and the herbal antidepressant berberin.{21423} PRE-084 is a high affinity, sigma receptor agonist, selective for the σ1 subtype (Kis = 2.2 and 13,091 nM for σ1 and σ2 receptors, respectively).{21420} It is a potent ligand of the σ receptor (IC50 = 44 nM) without appreciable affinity for PCP receptors (IC50 > 100,000 nM).{21420} PRE-084 has nootropic and antidepressant actions in vivo, as well as antitussive and reinforcing effects.{21424,21421,21425,21422}
Size 10 mg
Shipping dry ice
CAS Number 75136-54-8
Molecular Formula C19H27NO3 • HCl
SMILES O=C(OCCN1CCOCC1)C2(CCCCC2)C3=CC=CC=C3.Cl
Molecular Weight 353,9
Formulation A crystalline solid
Purity ≥98%
Custom Code 3822.19
UNSPSC code 12352100

Click here to ask for your quote and get 15% off Cayman's products.

 

Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.

/ We also advise you

Cross selling for this product : PRE-<wbr/>084 (hydro<wbr>chloride) There are 6 products.

Search