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KN-92 (hydrochloride)

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    KN-<wbr/>92 (hydro<wbr>chloride)
  • KN-<wbr/>92 (hydro<wbr>chloride)
Cat No: 9000890
Biochemicals - Kinase Inhibitors
Cayman

KN-92 is an inactive derivative of KN-93, the selective inhibitor of Ca2+/calmodulin-dependent kinase type II (CaMKII).{17325} At concentrations up to 25 μM, KN-92 is ineffective at inhibiting CaMKII or arresting cell growth of NIH 3T3 fibroblasts.{19...

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Territorial Availability: Available through Bertin Technologies only in France
Synonyms:
  • 2-[N-(4-methoxybenzenesulfonyl)]amino-N-(4-chlorocinnamyl)-N-methylbenzylamine, monohydrochloride
Correlated keywords:
  • Ca2+/calmodulin-dependents kinases II CaMKII KN-93 controls cells cycles inhibitors inhibited inhibition NIH 3T3 13319 inhibits KN92 KN 92 KN93 KN 93 176708-42-2
Product Overview:
KN-92 is an inactive derivative of KN-93, the selective inhibitor of Ca2+/calmodulin-dependent kinase type II (CaMKII).{17325} At concentrations up to 25 μM, KN-92 is ineffective at inhibiting CaMKII or arresting cell growth of NIH 3T3 fibroblasts.{19487} It is intended to be used as a control compound in studies designed to elucidate the antagonist activities of KN-93 (Item No. 13319).
Size 1 mg
Shipping dry ice
CAS Number 1431698-47-3
Molecular Formula C24H25ClN2O3S • HCl
SMILES CN(C/C=C/C1=CC=C(Cl)C=C1)CC2=CC=CC=C2N(S(=O)(C3=CC=C(OC)C=C3)=O)[H].O=P(OO)=O.[HH]
Molecular Weight 493,4
Formulation A crystalline solid
Purity ≥98%
Custom Code 2930.90
UNSPSC code 12352100

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

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ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.

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