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PPAR? Polyclonal Antibody

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    PPAR? Polyclonal Antibody
  • PPAR? Polyclonal Antibody
Cat No: 101720
Cayman

PPARδ is one of three peroxisome proliferator-activated receptor (PPAR) subtypes that possess a domain structure common to other members of the nuclear receptor gene family. It was first cloned from Xenopus laevis and named PPARβ.{1502} PPARδ is ubiqu...

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: 1 ea

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Territorial Availability: Available through Bertin Technologies only in France
Correlated keywords:
  • PPAR.delta. PPAR.beta. PPARbeta peroxisome proliferator-activated receptors PPARdelta antibodies antisera nuclear receptors antiserum western blots blotting WB ICC immunocytochemistry IHC immunohistochemistry atherosclerosis endocrinology immunoblotting antibodies
Product Overview:
PPARδ is one of three peroxisome proliferator-activated receptor (PPAR) subtypes that possess a domain structure common to other members of the nuclear receptor gene family. It was first cloned from Xenopus laevis and named PPARβ.{1502} PPARδ is ubiquitously expressed but is particularly abundant in tissues such as liver, intestine, kidney, abdominal adipose, and skeletal muscle, all of which are involved in lipid metabolism.{10670} PPARδ is a mediator of diverse physiological functions including lipid and cholesterol homeostasis, embryo implantation, and cancer development.{6570,7166,9142,7771} Most recently, attention has been focused on the role of PPARδ in obesity.{11581} Cayman’s PPARδ polyclonal antibody can be used for Western blot and immunohistochemistry to study the expression and functions of this protein. The antibody recognizes PPARδ at 50 kDa from human samples. An additional smaller size of PPARδ (~ 40 kDa){12236} is also detected in certain mouse tissues.
Size 1 ea
Shipping dry ice
Host Rabbit
Antigen Synthetic peptide from the N-terminal region of human PPAR?
Application(s)

IHC and WB

Formulation 500 µl Peptide affinity-purified antibody
Custom Code 3822.19
UNSPSC code 12352203

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.

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