Confirm delete?

Bertin Bioreagent
logo
All categories
Contact Us

Carnosol

  • Zoom
    Carnosol
  • Carnosol
Cat No: 89800
Biochemicals - Natural Products
Cayman

Carnosol is a phenol that has been found in rosemary (R. officinalis) and has diverse biological activities.{8781,6842,53877,6784} It decreases nitric oxide (NO) production in mouse peritoneal exudate macrophages when used at concentrations ranging fr...

More

This product can only be bought through Cayman Chemical. Please contact us.

Territorial Availability: Available through Bertin Technologies only in France
Synonyms:
  • 1,3,4,9,10,10aS-hexahydro-5,6-dihydroxy-1,1-dimethyl-7-isopropyl-2H-9S,4aR-(epoxymethano)phenanthren-12-one
Correlated keywords:
  • NSC39143 Picrosalvin Rosmarinus 5LO Polymorpho-nuclear
Product Overview:
Carnosol is a phenol that has been found in rosemary (R. officinalis) and has diverse biological activities.{8781,6842,53877,6784} It decreases nitric oxide (NO) production in mouse peritoneal exudate macrophages when used at concentrations ranging from 6 to 25 µM.{8781} Carnosol scavenges peroxyl and hydroxyl radicals and inhibits lipid peroxidation in cell-free assays.{6842} It inhibits 5-lipoxygenase (5-LO; IC50 = 0.1 µM for the recombinant human enzyme) and the synthesis of leukotrienes in human polymorphonuclear leukocytes (PMNs; IC50 = 7 µM).{53877} In vivo, carnosol (200 mg/kg) reduces mammary DNA adduct formation and tumorigenesis in a rat model of DMBA-induced mammary tumorigenesis.{6784}
Size 1 mg
Shipping dry ice
CAS Number 5957-80-2
Molecular Formula C20H26O4
SMILES CC(C)c1cc2C3OC(=O)C4(CCCC(C)(C)C4C3)c2c(O)c1O
Molecular Weight 330,4
Formulation A crystalline solid
Purity ≥98%
Custom Code 2907.29
UNSPSC code 12352100

Click here to ask for your quote and get 15% off Cayman's products.

 

Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.

/ We also advise you

Cross selling for this product : Carnosol There are 10 products.

Search