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Arachidonyl Trifluoromethyl Ketone

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    Arachidonyl Trifluoro<wbr/>methyl Ketone
  • Arachidonyl Trifluoro<wbr/>methyl Ketone
Cat No: 62120
Biochemicals - Small Molecule Inhibitors
Cayman

ATK is an analog of arachidonic acid in which the carboxyl group is replaced by a trifluoromethyl ketone group.{929} It inhibits the activity of the 85 kDa cPLA2 and the 80 kDa macrophage iPLA2 without altering the activity of the 14 kDa sPLA2s.{929,1...

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This product can only be bought through Cayman Chemical. Please contact us.

Territorial Availability: Available through Bertin Technologies only in France
Synonyms:
  • 1,1,1-trifluoro-6Z,9Z,12Z,15Z-heneicosatetraen-2-one
Correlated keywords:
  • ATK AACOCF3 inhibitors PLA2 analogs fatty acids lipoxygenases inhibition inhibits LOs neurochemistry neuroscience
Product Overview:
ATK is an analog of arachidonic acid in which the carboxyl group is replaced by a trifluoromethyl ketone group.{929} It inhibits the activity of the 85 kDa cPLA2 and the 80 kDa macrophage iPLA2 without altering the activity of the 14 kDa sPLA2s.{929,1291,2992} ATK is useful for differentiating the effects of cPLA2 and iPLA2 from sPLA2.{1530,1531}
Size 5 mg
Shipping dry ice
CAS Number 149301-79-1
Molecular Formula C21H31F3O
SMILES CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)C(F)(F)F
Molecular Weight 356,5
Formulation A solution in ethanol
Purity ≥98%
Custom Code 2909.49
UNSPSC code 12352100

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.

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