Sucralfate

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Sucralfate

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Cat No: 27882

Biochemicals - More Biochemicals

Sucralfate is a basic aluminum sucrose sulfate complex that has gastroprotective activity.{46263} It inhibits rat pepsin in a concentration-dependent manner and pepsin activity in isolated human gastric juice. It also inhibits ulcer formation induced ...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

hexadeca-?-hydroxytetracosahydroxy[?8-[[1,3,4,6-tetra-O-sulfo-?-D-fructofuranosyl ?-D-glucopyranoside tetrakis(sulfato-?O')](8-)]]hexadeca-aluminum

Correlated keywords:

Antepsin Carafate Citogel Hexagastron Keal Succosa Sucralafate Sucralfin Sucrate Sugast Sulcrate Ulcar Ulcerlmin Ulcermin Ulcogant Urbal Venter

Product Overview:
Sucralfate is a basic aluminum sucrose sulfate complex that has gastroprotective activity.{46263} It inhibits rat pepsin in a concentration-dependent manner and pepsin activity in isolated human gastric juice. It also inhibits ulcer formation induced by pyloric ligation, indomethacin (Item No. 70270), or cysteamine (Item No. 22193) in rats. Sucralfate (5,600 mg/animal) is protective against neutral ethanol and acidified taurocholic acid-induced damage in a rat model of hydrochloric acid-induced gastric mucosal damage, increasing the pH and reducing the disappearance of hydrogen ions.{46264} Formulations containing sucralfate have been used as antacids in the treatment of duodenal ulcer.

Size	500 mg
Shipping	dry ice
CAS Number	54182-58-0
Molecular Formula	C₁₂H₅₄Al₁₆O₇₅S₈
SMILES	O=S(OC[C@@H]1[C@@H](OS(=O)([O-][Al+3]2([OH-][Al+3]([OH-])([OH-])[OH-]2)[OH-])=O)[C@H](OS(=O)([O-][Al+3]3([OH-][Al+3]([OH-])([OH-])[OH-]3)[OH-])=O)[C@](COS(=O)([O-][Al+3]4([OH-][Al+3]([OH-])([OH-])[OH-]4)[OH-])=O)(O[C@@]5([H])O[C@H](COS(=O)([O-][Al+3]6([OH
Molecular Weight	2086,7
Formulation	A solid
Purity	≥95%
Custom Code	2930.90
UNSPSC code	12352100

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.