Oleic Acid-13C

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Oleic Acid-¹³C

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Cat No: 27869

Biochemicals - Isotopically Labeled Standards

Oleic acid-13C is intended for use as an internal standard for the quantification of oleic acid (Item Nos. 90260
24659) by GC- or LC-MS. Oleic acid is a monounsaturated fatty acid and a major component of membrane phospholipids that has been found i...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

9Z-octadecenoic-1-13C acid

Correlated keywords:

13 C 9 Z GCMS LCMS phospho-lipids mono-un-saturated phosphatidyl-choline MLF intra-cellular TNF? IL6 IL8 IL1? octa-decenoic deuterated deuterium

Product Overview:
Oleic acid-13C is intended for use as an internal standard for the quantification of oleic acid (Item Nos. 90260
24659) by GC- or LC-MS. Oleic acid is a monounsaturated fatty acid and a major component of membrane phospholipids that has been found in human plasma, cell membranes, and adipose tissue.{3964,42296} It contributes approximately 17% of the total fatty acids esterified to phosphatidylcholine, the major phospholipid class in porcine platelets.{3964} Oleic acid inhibits collagen-stimulated platelet aggregation by approximately 90% when used at a concentration of 10 µg/ml. It also inhibits fMLF-induced neutrophil aggregation and degranulation by 55 and 68%, respectively, when used at a concentration of 5 µM, similar to arachidonic acid (Item Nos. 90010
90010.1
10006607).{2095} Oleic acid (60 µM) induces release of intracellular calcium in human platelets.{4198} In vivo, oleic acid increases TNF-α, IL-8, IL-6, and IL-1β production, neutrophil accumulation, and apoptotic and necrotic cell death in mouse lung and has been used to induce lung injury in a mouse model of acute respiratory distress syndrome (ARDS).{42296}

Size	1 mg
Shipping	dry ice
CAS Number	82005-44-5
Molecular Formula	C₁₇[¹³C]H₃₄O₂
SMILES	CCCCCCCC/C=C\CCCCCCC[13C](O)=O
Molecular Weight	283,5
Formulation	A solution in ethanol
Purity	≥98%
Custom Code	3822.19
UNSPSC code	12352100

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.