Pyridoxatin

Pyridoxatin

CAT N°: 27607
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122.00 103.70

Pyridoxatin is a fungal metabolite originally isolated from Acremonium with diverse biological activities.{43929} It inhibits production of thiobarbituric acid reactive substance (TBARS) in vitro (IC50 = 0.55 ?g/ml). Pyridoxatin inhibits hemolysis induced by the free radical generator AAPH in rat erythrocytes (IC50 = 1.95 ?g/ml). It is active against C. albicans (MIC = 1.64 ?g/ml). Pyridoxatin is cytotoxic in a panel of 21 cancer cell lines (EC50s = 0.10-7.04 ?g/ml).{43930} It also inhibits gelatinase A (IC50 = 15.2 ?M).

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