23-hydroxy Betulinic Acid

Biochemicals - Natural Products

Zoom

Cat No: 27446

Biochemicals - Natural Products

23-hydroxy Betulinic acid is a triterpenoid that has been found in P. chinensis and has anticancer activity.{42830} It inhibits proliferation of K562, B16, and HeLa cells (IC50s = 39.9, 78.5, and 80 µM, respectively), as well as human umbilical vein e...

This product can only be bought through Cayman Chemical. Please contact us.

Product Overview
Data
Downloads
About Cayman

Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

(3?,4?)-3,23-dihydroxy-lup-20(29)-en-28-oic acid

Correlated keywords:

Anemosapogenin Anemo-sapogenin Dihydroxylup Hydroxybetulinic 23HBA B4-G2 anti-cancer tri-terpenoid K-562 B-16 B4G2 Pulsatilla

Product Overview:
23-hydroxy Betulinic acid is a triterpenoid that has been found in P. chinensis and has anticancer activity.{42830} It inhibits proliferation of K562, B16, and HeLa cells (IC50s = 39.9, 78.5, and 80 µM, respectively), as well as human umbilical vein endothelial cells (HUVECs; IC50 = 94.8 µM). It halts the cell cycle at the S phase and induces apoptosis in K562 cells in a concentration-dependent manner with a loss of the mitochondrial membrane potential and an increase in Bax and cytochrome C protein levels.

Size	1 mg
Shipping	dry ice
CAS Number	85999-40-2
Molecular Formula	C₃₀H₄₈O₄
SMILES	CC([C@@H]1CC[C@]2(C(O)=O)CC[C@@]3(C)[C@]4(C)CC[C@@]5([H])[C@@](CO)(C)[C@@H](O)CC[C@]5(C)[C@@]4([H])CC[C@]3([H])[C@]21[H])=C
Molecular Weight	472,7
Formulation	A solid
Purity	≥98%
Custom Code	2918.99
UNSPSC code	12352100

Technical File

MSDS

Click here to ask for your quote and get 15% off Cayman's products.

Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.

/ We also advise you

Cross selling for this product : 23-hydroxy Betulinic Acid There are 2 products.