ACTH (1-13) (human, mouse, rat,

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ACTH (1-13) (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt)

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Cat No: 27150

Biochemicals - Peptides

ACTH (1-13) is a peptide fragment of adrenocorticotropic hormone (ACTH; Item No. 24257), a peptide hormone found in the brain that is involved in the biological stress response.{45140} An acetylated form of ACTH (1-13), α-melanocyte stimulating hormon...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

?1-13-corticotropin, trifluoroacetate salt

Correlated keywords:

17088-02-7 22006-64-0 H-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-OH SYSMEHFRWGKPVOH AC TH ?MSH MC 3R 4R AMP Melanotropin Tridecactide

Product Overview:
ACTH (1-13) is a peptide fragment of adrenocorticotropic hormone (ACTH; Item No. 24257), a peptide hormone found in the brain that is involved in the biological stress response.{45140} An acetylated form of ACTH (1-13), α-melanocyte stimulating hormone (α-MSH), is formed in the intermediate lobe of the pituitary gland by cleavage of ACTH (1-39), as well as in keratinocytes, astrocytes, monocytes, and gastrointestinal cells.{45140,47500} ACTH (1-13) is an agonist of melanocortin receptor 3 (MC3R) and MC4R, inducing cAMP production in vitro with EC50 values of 0.18 and 19 nM, respectively, which is similar in potency to that of α-MSH.{45139} It induces differentiation of melanocytes when used at concentrations ranging from 0.001 to 1,000 nM.{48426} ACTH (1-13) (40 and 400 pmol, i.c.v.) decreases food intake in broiler chicks.{47501}

Size	1 mg
Shipping	dry ice
Molecular Formula	C₇₅H₁₀₆N₂₀O₁₉S • XCF₃COOH
SMILES	[H]N[C@@H](CO)C(N[C@H](C(N[C@@H](CO)C(N[C@H](C(N[C@@H](CCC(O)=O)C(N[C@H](C(N[C@H](C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(NCC(N[C@@H](CCCCN)C(N1CCC[C@H]1C(N[C@@H](C(C)C)C(O)=O)=O)=O)=O)=O)CC2=CNC3=C2C=CC=C3)=O)=O)CC4=CC=CC=C4)=O)CC5=CN=CN5)=O)=O)CCSC)=O)=O)CC6=CC
Molecular Weight	1623,8
Formulation	A solid
Purity	≥98%
Custom Code	3504.00
UNSPSC code	12352100

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