Pal-GHK

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Pal-GHK

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Cat No: 27059

Biochemicals - Peptides

Pal-GHK is a form of the extracellular matrix-derived peptide GHK (Item No. 27168) containing palmitic acid (Item No. 10006627), which allows it to penetrate the stratum corneum to the epidermal and dermal skin layers.{42842} Pal-GHK (0.5 µM) increase...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

N-(1-oxohexadecyl)glycyl-L-histidyl-L-lysine

Correlated keywords:

Palmitoylglycylhistidyllysine Palmitoyl Biopeptide-CL C-16 C16-GK3 C16GK3 C16GHK PalGHK C12-DMAO palKTTKS antiwrinkle 844471-26-7 tripeptide LCMS

Product Overview:
Pal-GHK is a form of the extracellular matrix-derived peptide GHK (Item No. 27168) containing palmitic acid (Item No. 10006627), which allows it to penetrate the stratum corneum to the epidermal and dermal skin layers.{42842} Pal-GHK (0.5 µM) increases collagen synthesis in human skin fibroblasts in vitro. It reduces collagen degradation ex vivo in patient-derived human skin samples irradiated with UVA light when used at a concentration of 6 ppm. It has been used with the zwitterionic surfactant C12 dodecyldimethylamine oxide (C12DMAO) to study self-assembly of the mixture into aggregates, ribbons, and nanobelts.{42843,42844} Pal-GHK has also been used as an internal standard for the quantification of pal-KTTKS in anti-wrinkle creams by LC-MS/MS.{42845}

Size	100 mg
Shipping	dry ice
CAS Number	147732-56-7
Molecular Formula	C₃₀H₅₄N₆O₅
SMILES	O=C(N[C@H](C(O)=O)CCCCN)[C@@H](NC(CNC(CCCCCCCCCCCCCCC)=O)=O)CC1=CN=CN1
Molecular Weight	578,8
Formulation	A solid
Purity	≥95%
Custom Code	2933.29
UNSPSC code	12352100

Technical File

MSDS

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.