20(R)-Protopanaxadiol

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Cat No: 25052

Biochemicals - Natural Products

(20)R-Protopanaxadiol is a sapogenin that has been found in P. ginseng and has anticancer and antibacterial activities.{36822,36823,36824} It has a cytotoxic concentration (CC50) value of 6.1 µM in MT-4 human T cell leukemia cells and inhibits the gro...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

dammar-24-ene-3?,12?,20R-triol

Correlated keywords:

11045-17-3 20R 20(R)-APPD PPD anti-cancer bacterial Panax A-549 SK-OV-3 SKOV-3 SKMel2 SKMel-2 P-388 L-1210 K-562 helicobacter MT4

Product Overview:
(20)R-Protopanaxadiol is a sapogenin that has been found in P. ginseng and has anticancer and antibacterial activities.{36822,36823,36824} It has a cytotoxic concentration (CC50) value of 6.1 µM in MT-4 human T cell leukemia cells and inhibits the growth of several additional cancer cell lines, including A549 human lung carcinoma, SKOV3 human ovarian adenocarcinoma, SK-Mel-2 human melanoma, P388 and L1210 murine leukemia, and K562 human chronic leukemia cells (ED50s = 11-26 µM).{36822,36823} (20)R-protopanaxadiol also inhibits the growth of H. pylori in vitro (MICs = 50-100 µg/ml).{36824}

Size	5 mg
Shipping	dry ice
CAS Number	03/01/7755 00:00
Molecular Formula	C₃₀H₅₂O₃
SMILES	CC1(C)[C@@H](O)CC[C@@]2(C)[C@@]1([H])CC[C@]3(C)[C@]2([H])C[C@@H](O)[C@@]4([H])[C@@]3(C)CC[C@]4([H])[C@@](O)(C)CC/C=C(C)/C
Molecular Weight	460,7
Formulation	A crystalline solid
Purity	≥98%
Custom Code	2902.90
UNSPSC code	12352100

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MSDS

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.