C18 Ganglioside GD3-d3 (ammonium

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C18 Ganglioside G_D3-d₃ (ammonium salt)

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Cat No: 24852

Biochemicals - Isotopically Labeled Standards

C18 Ganglioside GD3-d3 is intended for use as an internal standard in the quantification of ganglioside GD3 (Item No. 17481) by GC- or LC-MS. Ganglioside GD3 is synthesized by the addition of two sialic acid residues to lactosylceramide (Item No. 1698...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

N-[(1S,2R,3E)-1-[[[O-(N-acetyl-?-neuraminosyl)-(2?8)-O-(N-acetyl-?-neuraminosyl)-(2?3)-O-?-D-galactopyranosyl-(1?4)-?-D-glucopyranosyl]oxy]methyl]-2-hydroxy-3-heptadecen-1-yl]-octadecanamide-18,18,18-d3, diammonium salt

Correlated keywords:

2692624-23-8 151636-13-4 deuterated deuterium GCMS LCMS

Product Overview:
C18 Ganglioside GD3-d3 is intended for use as an internal standard in the quantification of ganglioside GD3 (Item No. 17481) by GC- or LC-MS. Ganglioside GD3 is synthesized by the addition of two sialic acid residues to lactosylceramide (Item No. 16983) and can serve as a precursor to the formation of more complex gangliosides by the action of glycosyl- and sialyltransferases. With roles in cell proliferation and differentiation, its expression increases during development and in pathological conditions such as cancer.{28470} Furthermore, the intracellular accumulation of ganglioside GD3 can contribute to mitochondrial damage, a crucial event during apoptosis.{5033} Ganglioside GD3 has become a target for therapeutic approaches to prevent malignant properties of tumor cells like melanoma.{28470,28471} [Matreya, LLC. Catalog No. 2054]

Size	500 µg
Shipping	dry ice
CAS Number	2692624-24-9
Molecular Formula	C₇₀H₁₂₀D₃N₃O₂₉ • 2NH₄
SMILES	OC[C@H]1O[C@@H](OC[C@H](NC(CCCCCCCCCCCCCCCCC([2H])([2H])[2H])=O)[C@H](O)/C=C/CCCCCCCCCCCCC)[C@H](O)[C@@H](O)[C@@H]1O[C@]2([H])O[C@H](CO)[C@H](O)[C@H](O[C@@]3(C([O-])=O)O[C@@H]([C@H](O)[C@H](O[C@@]4(C([O-])=O)O[C@@H]([C@H](O)[C@@H](CO)O)[C@H](NC(C)=O)[C@@H
Molecular Weight	1509,8
Formulation	A solid
Purity	≥99% deuterated forms (d1 -d3)
Custom Code	3822.19
UNSPSC code	12352100

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C18 Ganglioside GD3-d3 (ammonium salt)