Allethrin

Confirm delete?

Allethrin

Zoom

Cat No: 24132

Biochemicals - Pesticides

Allethrin is a pyrethroid insecticide and modulator of voltage-gated sodium channels (NaV).{39796} It delays channel deactivation in cockroach giant axons when used at a concentration of 1 μM. Allethrin is 100-fold more potent at insect than rat NaV1....

This product can only be bought through Cayman Chemical. Please contact us.

Product Overview
Data
Downloads
About Cayman

Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

2,2-dimethyl-3-(2-methyl-1-propen-1-yl)-cyclopropanecarboxylic acid, 2-methyl-4-oxo-3-(2-propen-1-yl)-2-cyclopenten-1-yl ester

Correlated keywords:

137-98-4 6385-67-7 6385-68-8 8018-12-0 18793-35-6 18877-88-8 20301-61-5 22431-63-6 22556-34-9 23453-08-9 24313-23-3 25406-22-8 25406-24-0 25406-25-1 71119-51-2 71211-88-6 84030-86-4 NaV-1.8 Allethrin Allethrine Depallethrin Depallethrine EBT ENT17510 Exthrin Matox Pynamin Pyresyn RU27436 OMS3045 NSC11782 Wasp Stopper CF d-T80 dT80 T-80 dl ENT 17510 Allyl cinerin I OMS 3045

Product Overview:
Allethrin is a pyrethroid insecticide and modulator of voltage-gated sodium channels (NaV).{39796} It delays channel deactivation in cockroach giant axons when used at a concentration of 1 μM. Allethrin is 100-fold more potent at insect than rat NaV1.8 channels expressed in Xenopus oocytes.{36375} It decreases egg production by and is lethal to mosquitoes (LC50 = 0.01%).{39797} Allethrin induces production of reactive oxygen species (ROS), lipid peroxidation, and apoptosis in rat primary Leydig cells.{39798} In vivo, the smoke of an allethrin-based mosquito coil increases levels of the hepatic enzymes ALT and AST and induces hepatocyte apoptosis as well as emphysema and lung hyperplasia in mice.{39799}

Size	50 mg
Shipping	dry ice
CAS Number	584-79-2
Molecular Formula	C₁₉H₂₆O₃
SMILES	C/C(C)=C/C1C(C)(C)C1C(OC2C(C)=C(CC=C)C(C2)=O)=O
Molecular Weight	302,4
Formulation	An oil
Purity	≥95%
Custom Code	2914.50
UNSPSC code	12352100

Technical File

MSDS

Click here to ask for your quote and get 15% off Cayman's products.

Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.