Xenobiotic biotransformation is the principal mechanism for maintaining homeostasis during organism exposure to foreign molecules such as drugs. It is accomplished by a limited number of enzymes with broad substrate specificities, such as CYP450 enzymes.
Being the major elimination route for many drugs, CYP450 enzymes play a very important role in the xenobiotics detoxication, but may also lead to toxic or tumorigenic metabolites.
Those metabolites are either produced by chemical synthesis or by biotransformation – biocatalysis reactions. Upon request, Bertin Bioreagent can provide you with bulk quantities of any of those biochemicals.
Explore your options with our broad spectrum of products dedicated to metabolism studies such as:
Bertin Bioreagent also proposes a fully integrated analytical and preparative platform using chemical synthesis, biotransformation or chemoenzymatic technologies for the production of conjugated metabolites.