β-Naphthoflavone

β-Naphthoflavone

CAT N°: 34040
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From 48.00 40.80

?-Naphthoflavone is a non-carcinogenic agonist of the aryl hydrocarbon receptor (AhR).{54964} It activates transcription of the AhR target gene CYP1A1 when used at concentrations of 1 and 10 µM in HepG2 cells.{54964} ?-Naphthoflavone (10 µM) inhibits hydrogen peroxide-induced apoptosis, as well as increases the activity of catalase (CAT) and superoxide dismutase (SOD) and decreases the levels of malondialdehyde (MDA), in SH-SY5Y cells.{54965} It has also been used as a positive control for the induction of AhR transcriptional activity.{54964}

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