Bertin Bioreagent introduces Myelotracker®, an innovative peptide-based probe specifically designed to target lactoferrin, a major protein stored in neutrophil-specific granules. By binding to lactoferrin, Myelotracker® enables the precise detection and visualization of neutrophils, both in fixed tissues and in live cell assays. 

A key advantage of this probe is that it does not activate neutrophils, thereby preserving their physiological state and ensuring reliable and reproducible results. Myelotracker has a dual application, labeling intracellular granules in fixed samples. Also, it detects extracellular lactoferrin released upon neutrophil activation, making it a unique tool for studying both resting and activating neutrophils. 

The probe has been validated across multiple species, including human, mouse, rabbit, and guinea pig, demonstrating its robustness and versatility. It is fully compatible with a wide range of techniques such as tissue imaging, flow cytometry, in vitro assays, and in vivo models of inflammation or infection. 

By integrating Myelotracker into its Bioreagent portfolio, Bertin provides the scientific community with a powerful and reliable solution for advancing immunology and inflammation research and for gaining deeper insights into neutrophil biology.