LY3000328

LY3000328

CAT N°: 29729
Price:

122.00 103.70

LY3000328 is a potent cathepsin S inhibitor (IC50 = 7.7 nM for the human enzyme).{53427} It is selective for cathepsin S over cathepsin L, K, B, and V (IC50s = >10,000, >10,000, 4,390, and 21,500 nM, respectively). LY3000328 (1-30 mg/kg) reduces aortic diameter in a mouse model of calcium chloride-induced abdominal aortic aneurysm.

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