L-Tryptophan

L-Tryptophan

CAT N°: 29600
Price:

49.00 41.65

L-Tryptophan is an essential amino acid.{53275} It serves as a substrate for tryptophan hydroxylase (TPH), indoleamine-2,3-dioxygenase (IDO), and tryptophan-2,3-dioxygenase (TDO) for the biosynthesis of serotonin (5-HT; Item No. 14332) and kynurenine (Item No. 11305).{53276} L-Tryptophan is also metabolized by enteric bacteria expressing tryptophanase into indole, pyruvate, and ammonia.{53033} It increases 5-HT, 5-hydroxy-L-tryptophan (5-HTP; Item No. 20539), and 5-hydroxyindolacetic acid (5-HIAA; Item No. 22889) levels in the diencephalon of rats when administered at a dose of 300 mg/kg.{53277} L-Tryptophan decreases immobility time in the forced swim test in rats when administered at doses of 4 and 20 mg/kg per day for eight weeks.{53278}

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