Amyloid-? (1-8, A2V) Peptide
Amyloid-? (1-8, A2V) Peptide
Amyloid-? (1-8, A2V) is a truncated form of amyloid-? (A?) that contains a valine to alanine substitution at position 2...
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From €85.00 €72.25
IOWH-032 is a modulator of the cystic fibrosis transmembrane conductance regulator (CFTR).{58097,58098} It inhibits CFTR in T84 human colon cells (IC50 = 8.51 µM).{58097} It has rapid inhibitory and slow potentiating effects on human CFTR with apparent Kd values of 6.1 and 0.64 nM, respectively.{58098} IOWH-032 (20 nM) also potentiates currents through CFTR bearing the F508 deletion mutation (?F508-CFTR) expressed in X. laevis oocytes. It inhibits, but does not potentiate, mouse CFTR with an apparent Kd value of 42.9 µM.
Territorial Availability: Available through Bertin Technologies only in France
| Size | 10 mg, 25 mg, 5 mg, 50 mg |
|---|---|
| Shipping | dry ice |
| CAS number | 1191252-49-9 |
| Molecular formula | C22H15Br2N3O4 |
| Smiles | O=C(C1=NC(C2=CC(Br)=C(O)C(Br)=C2)=NO1)NCC(C=C3)=CC=C3OC4=CC=CC=C4 |
| Molecular weight | 545,2 |
| Custom code | 2924.29 |
| Formulation | A crystalline solid |
| Purity | ≥98% |
| UNSPSC code | 12352100 |
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Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.
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