Vasoactive Eicosanoid HPLC Mixture
Vasoactive Eicosanoid HPLC Mixture
This mixture contains the characteristic metabolites of both PGI2 and TXA2. Contents: Thromboxane B2, 11-dehydro Thromboxane B2, 6-keto Prostaglandin F1?,...
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Inosine is a purine nucleoside composed of hypoxanthine (Item No. 22254) and ribose.{58936} It is formed from inosine-5′-monophosphate (Item No. 18135) by 5′-nucleotidase.{58937} Inosine can also be formed by the deamination of adenosine, a post-translational modification known as A-to-I editing that occurs in tRNA and mRNA and is catalyzed by adenosine deaminase acting on RNA (ADAR).{58936} It inhibits the production of TNF-?, IL-1, and IL-12 in LPS-stimulated isolated mouse peritoneal macrophages when used at concentrations ranging from 30 to 1,000 µM.{58938} Inosine reduces sensorimotor impairments in a rat model of cerebral ischemia induced by middle cerebral artery occlusion (MCAO) when administered as a continuous infusion into the cisterna magna via osmotic minipump.{58939}
Territorial Availability: Available through Bertin Technologies only in France
| Size | 10 g, 100 ?g, 5 g, 50 g |
|---|---|
| Shipping | dry ice |
| CAS number | 58-63-9 |
| Molecular formula | C10H12N4O5 |
| Smiles | O[C@H]1[C@](O[C@@H]([C@H]1O)CO)([H])N2C3=C(C(N=CN3)=O)N=C2 |
| Molecular weight | 268,2 |
| Custom code | 2934.99 |
| Formulation | A solid |
| Purity | ≥98% |
| UNSPSC code | 12352100 |
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