Hydroflumethiazide-<sup>13</sup>C-d<sub>2</sub>

Hydroflumethiazide-13C-d2

CAT N°: 31608
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Hydroflumethiazide-13C-d2 is intended for use as an internal standard for the quantification of hydroflumethiazide (Item No. 23612) by GC- or LC-MS. Hydroflumethiazide is a thiazide diuretic and an inhibitor of carbonic anhydrase (CA).{23242} It is selective for CAII, CAVB, CAVII, CAIX, CAXII, and CAXIV (Kis = 0.24-0.31 µM) over CAI, CAIV, and CAVI (Kis = 2.8-8.3 µM), as well as CAIII, CAVA, and CAXIII (Kis = >10 µM). Formulations containing hydroflumethiazide have been used in the treatment of hypertension.

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