Decitabine

Decitabine

CAT N°: 11166
Price:

From 71.00 60.35

5-Azacytidine is an analog of cytidine which can be incorporated into DNA, inhibit DNA methyltransferases, and cause hypomethylation of cytosine residues in the absence of any significant mutagenic effects.{18356,18373} Decitabine is a 2’-deoxy analog of 5-azacytidine which similarly causes hypomethylation of DNA by inhibiting DNA methyltransferases in a concentration-dependent manner.{18356,18373,17257} This action is useful in conditions characterized by DNA hypermethylation, as is found in myelodysplastic syndromes.{20547}

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