AT-130

AT-130

CAT N°: 35453
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AT-130 is an antiviral agent.{65209,65210} It is a non-nucleoside inhibitor of hepatitis B virus (HBV) replication in wild-type and rtL180M, rtM204I, and rtL180M + rtL204V lamivudine-resistant strains of HBV (IC50s = 2.4, 1.6, 5.1, and 1.3 µM, respectively).{65210} AT-130 inhibits viral DNA synthesis in HBV-infected HepAD38 cells (EC50 = 0.13 µM) and reduces the amount of encapsidated RNA in HBV-infected HepG2 cells.{65210,65211}

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