Apixaban

Apixaban

CAT N°: 15427
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Apixaban is an orally bioavailable, selective inhibitor of both free and prothrombinase-bound factor Xa (Kis = 0.8 nM).{25094} In vivo, apixaban has antithrombotic effects in a rabbit model of venous thrombosis. Apixaban (357.5 mg) also prevents thrombus formation without inducing adverse bleeding events in a porcine model of aortic heterotopic valve replacement.{36697} Formulations containing apixaban have been used to prevent blood clot formation in patients with atrial fibrillation.

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