ACPT-<wbr/>II

ACPT-II

CAT N°: 78020
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ACPT-II is a general competitive antagonist of metabotropic glutamate (mGlu) receptors. The KB values for mGlu1a, mGlu2, and mGlu4a receptors are 115, 88, and 77 µM, respectively.{5944} It binds to the large extracellular domain called a Venus flytrap module, where agonists bind.{30235} ACPT-II is a stereoisomer of the group III mGlu receptor-selective antagonist, ACPT-I.{5944}

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