Rhodojaponin III is a diterpenoid that has been found in R. molle and has insecticidal and antinociceptive activities.{57993,57992} It reduces pupation and the number of Colorado potato beetle (L. decemlineata) larvae on, and damage to, potato plants when applied at concentrations of 75 and 150 ppm.{57993} It also induces mortality in adult confused flour beetles (T. confusum). Rhodojaponin III has antinociceptive effects in mouse models of chemical, inflammatory, and neuropathic pain.{57992} It reduces acetic acid-induced writhing in mice (ID50 = 0.0469 mg/kg) and increases the paw withdrawal threshold for mechanical stimuli in a mouse model of diabetic peripheral neuropathic pain when administered at doses of 0.04 and 0.08 mg/kg. Rhodojaponin III is toxic to mice with an LD50 value of 0.271 mg/kg.
Territorial Availability: Available through Bertin Technologies only in France
| Size | 1 mg, 10 mg, 25 mg, 5 mg |
|---|---|
| Shipping | dry ice |
| CAS number | 26342-66-5 |
| Molecular formula | C20H32O6 |
| Smiles | O[C@H]1[C@@](C[C@H]2O)(C[C@]3(O)C)[C@](CC[C@]13[H])([H])[C@@](O)([C@@]([C@@](O4)([H])[C@@]4([H])C(C)5C)([H])[C@]25O)C |
| Molecular weight | 368,5 |
| Custom code | 2910.90 |
| Formulation | A solid |
| Purity | ≥98% |
| UNSPSC code | 12352100 |
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Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.
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