KRP 297

KRP 297

CAT N°: 33699
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KRP 927 is a thiazolidinedione dual agonist of PPAR? and PPAR? (EC50s = 149 and 83 nM, respectively, in transactivation assays).{59890} It decreases hyperglycemia and hyperinsulinemia in ob/ob mice in a dose-dependent manner. KRP 927 (10 or 30 mg/kg) reduces serum total cholesterol and triglyceride levels in hamsters.

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