From €102.00 €86.70
TunR2 is an antibiotic and derivative of tunicamycin (Item No. 11445).{54399} It is active against B. subtilis (MIC = 0.3 µg/ml) and increases the efficacy of the ?-lactam antibiotics oxacillin (Item No. 23954), methicillin (Item No. 21007), and penicillin G (Item No. 21615) against B. subtilis when used at a concentration of 0.4 ?g/ml. Unlike tunicamycin, TunR2 is non-toxic to S. cerevisiae (MIC = >10 ?g/ml) and does not inhibit glycosylation in a protein N-glycosylation assay. TunR2 also has reduced antiproliferative activity against MDA-MB-231 and CHO cells compared with tunicamycin.
Territorial Availability: Available through Bertin Technologies only in France
| Size | 1 mg, 500 µg |
|---|---|
| Shipping | dry ice |
| Molecular formula | C39H68N4O16 (for TunR2 16:0) |
| Smiles | CC(N[C@H]1[C@@H](O[C@H]2[C@H](NC(CCCCCCCCCCC(C)C)=O)[C@@H](O)[C@@H](O)[C@@H](C[C@@H](O)[C@@H]3[C@@H](O)[C@@H](O)[C@H](N4CCC(NC4=O)=O)O3)O2)O[C@H](CO)[C@@H](O)[C@@H]1O)=O.CC(N[C@H]5[C@@H](O[C@H]6[C@H](NC(CCCCCCCCCCCC(C)C)=O)[C@@H](O)[C@@H](O)[C@@H](C[C@@H](O)[C@@H]7[C@@H](O)[C@@H](O)[C@H](N8CCC(NC8=O)=O)O7)O6)O[C@H](CO)[C@@H](O)[C@@H]5O)=O.CC(N[C@H]9[C@@H](O[C@H][C@H](NC(CCCCCCCCCCCCC(C)C)=O)[C@@H](O)[C@@H](O)[C@@H](C[C@@H](O)[C@@H][C@@H](O)[C@@H](O)[C@H](NCCC(NC=O)=O)O)O)O[C@H](CO)[C@@H](O)[C@@H]9O)=O.CC(N[C@H][C@@H](O[C@H][C@H](NC(CCCCCCCCCCCCCC(C)C)=O)[C@@H](O)[C@@H](O)[C@@H](C[C@@H](O)[C@@H][C@@H](O)[C@@H](O)[C@H](NCCC(NC=O)=O)O)O)O[C@H](CO)[C@@H](O)[C@@H]O)=O |
| Molecular weight | |
| Custom code | 2938.90 |
| Formulation | A crystalline solid |
| Purity | ≥95% (mixture of congeners) |
| UNSPSC code | 12352100 |
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