Methylspin</wbr>azarin

Methylspinazarin

CAT N°: 29898
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From 342.00 290.70

Methylspinazarin is a naphthoquinone bacterial metabolite that has been found in Streptomyces and is an inhibitor of catechol O-methyltransferase (COMT; IC50 = 0.8 ?g/ml).{49489} It is selective for COMT over tyrosine hydroxylase, DOPA decarboxylase, and dopamine-?-hydroxylase at 100 ?g/ml. Methylspinazarin decreases blood pressure in spontaneously hypertensive rats when administered at a dose of 50 mg/kg.

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