From €91.00 €77.35
Panaxatriol is a sapogenin that has been found in P. ginseng and has diverse biological activities, including antiproliferative, cardioprotective, and antidiabetic properties.{52069,52070,52071} It inhibits the proliferation of DU15 prostate cancer cells (IC50 = 30 ?M) and induces apoptosis by increasing production of reactive oxygen species (ROS) and decreasing the mitochondrial membrane potential.{52069} Panaxatriol (5 mg/kg) reduces ischemia and reperfusion-induced myocardial dysfunction, increases left ventricular developed pressure (LVDevP) and glutathione (GSH) levels, and decreases cardiac lactate dehydrogenase (LDH), creatine kinase (CK), and malondialdehyde (MDA) levels in rats when administered for seven consecutive days prior to injury.{52070} Dietary administration of panaxatriol (0.2% for 6 weeks) decreases fasting blood glucose levels in KKAy insulin-resistant mice.{52071}
Territorial Availability: Available through Bertin Technologies only in France
| Size | 100 mg, 25 mg, 50 mg |
|---|---|
| Shipping | dry ice |
| CAS number | 32791-84-7 |
| Molecular formula | C30H52O4 |
| Smiles | CC1(C)[C@@H](O)CC[C@@]2(C)[C@@]1([H])[C@H](O)C[C@]3(C)[C@]2([H])C[C@@H](O)[C@@]4([H])[C@@]3(C)CC[C@]4([H])[C@]5(C)OC(C)(C)CCC5 |
| Molecular weight | 476,7 |
| Custom code | 2938.90 |
| Formulation | A solid |
| Purity | ≥95% |
| UNSPSC code | 12352100 |
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Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.
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