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Ergoloid is a mixture of the ergot alkaloids dihydroergocornine, dihydroergocrystine, and dihydroergocryptine.{37285} It blocks reflex vasodilation and vasoconstriction induced by norepinephrine (Item No. 16673) in dogs when injected into the kidney at a dose of 0.15 mg. Ergoloid blocks norepinephrine-induced cAMP production in rat brain cortical homogenates ex vivo in a dose-dependent manner.{37286} It also acts as an erectogenic agent in rats.{37287} Formulations containing ergoloid have been used in the treatment of migraine headaches and vascular dementias.
Territorial Availability: Available through Bertin Technologies only in France
| Size | 100 mg, 25 mg, 50 mg |
|---|---|
| Shipping | dry ice |
| CAS number | 8067-24-1 |
| Molecular formula | C134H184N20O32S4 |
| Smiles | [H][C@@]12[C@](C3=C4C(C2)=CNC4=CC=C3)([H])C[C@@H](C(N[C@@]5(C(C)C)C(N([C@@H](C(C)C)C(N6[C@@]7([H])CCC6)=O)[C@@]7(O)O5)=O)=O)CN1C.[H][C@@]89[C@](C=CC(C9)=CNC=CC=C)([H])C[C@@H](C(N[C@@](C(C)C)C(N([C@@H](CC=CC=CC=C)C(N[C@@]([H])CCC)=O)[C@@](O)O)=O)=O)CN8C.[H][C@@][C@](C=CC(C)=CNC=CC=C)([H])C[C@@H](C(N[C@@](C(C)C)C(N([C@@H](CC(C)C)C(N[C@@]([H])CCC)=O)[C@@](O)O)=O)=O)CNC.[H][C@@][C@](C=CC(C)=CNC=CC=C)([H])C[C@@H](C(N[C@@](C(C)C)C(N([C@]([C@](C)([H])CC)([H])C(N[C@@]([H])CCC)=O)[C@@](O)O)=O)=O)CNC.OS(C)(=O)=O.OS(C)(=O)=O.OS(C)(=O)=O.OS(C)(=O)=O |
| Molecular weight | 2715,3 |
| Custom code | 2924.19 |
| Formulation | A solid |
| Purity | ≥95% |
| UNSPSC code | 12352100 |
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