Enniatin B1

Enniatin B1

CAT N°: 17245
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Enniatins are cyclohexadepsipeptides commonly isolated from fungi and are known to have antibiotic properties. Many act as ionophores, forming pores in cellular membranes to allow selective ion transport.{24952,24954} Enniatin B1 is one of four major analogs of the enniatin complex (Item No. 9002040). It has been shown to induce apoptosis in several cancer lines (EC50s ? 10 µM) and to decrease the activation of the cell proliferation kinase, ERK (p44/p42).{24949} Enniatin B1 also inhibits the multi-drug resistance transporter Pdr5p from S. cerevisiae and has been used to examine drug resistance mechanisms.{24951}

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