From €359.00 €305.15
Lumula is a hybrid eicosanoid analog that incorporates the docosanoid and prostamide features of unoprostone (Item No. 16680) and bimatoprost (17-phenyl trinor Prostaglandin F2? ethyl amide; Item No. 16820), respectively, prostaglandin analogs that lack potency at the prostanoid FP receptor.{55268,19618,9658} Based on classical structure-activity relationships that have been established for prostanoid receptors, lumula is predicted to have low activity at these receptors.{8322} The N-ethyl amide prodrug moiety it inherits from bimatoprost is slow to hydrolyze and the lower side chain modifications inherited from unoprostone interfere with FP receptor binding.{9311,2058} Lumula is intended for use as a negative control for testing mechanisms of unoprostone and bimatoprost activity.
Territorial Availability: Available through Bertin Technologies only in France
| Size | 1 mg, 100 µg, 500 µg |
|---|---|
| Shipping | dry ice |
| CAS number | 511229-72-4 |
| Molecular formula | C24H43NO4 |
| Smiles | O[C@@H]1[C@H](C/C=CCCCC(N([H])CC)=O)[C@@H](CCC(CCCCCCC)=O)[C@H](O)C1, O[C@@H]1[C@H](C/C=CCCCC(N([H])CC)=O)[C@@H](CCC(CCCCCCC)=O)[C@H](O)C1, O[C@@H]1[C@H](C/C=CCCCC(N([H])CC)=O)[C@@H](CCC(CCCCCCC)=O)[C@H](O)C1 |
| Molecular weight | 409,6 |
| Custom code | 2937.50 |
| Formulation | A solution in methyl acetate |
| Purity | ≥98% |
| UNSPSC code | 12352100 |
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