ISX-<wbr/>9

ISX-9

CAT N°: 16165
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From 48.00 40.80

ISX-9 is a small molecule inducer of adult neural stem cell differentiation both in vitro and in vivo. At 2.5-20 µM, ISX-9 has been shown to dose-dependently trigger neurogenesis and block gliogenesis in adult rat hippocampal stem cells through a calcium-activated signaling pathway dependent on myocyte-enhancer factor 2-dependent gene expression.{26344,26345,26343} ISX-9 administered at 20 mg/kg for 12 days to mice has been reported to improve hippocampal function as evidenced by enhanced spatial memory ability in the Morris water maze test.{26343}

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