5'-deoxy Thymidine

5′-deoxy Thymidine

CAT N°: 18154
Price:

48.00 40.80

The pyrimidine thymidine consists of thymine combined with deoxyribose. Prior to polymerization into DNA, thymidine must be phosphorylated at the hydroxyl group on carbon 5 of the ribose moiety. 5′-deoxy Thymidine is a form of thymidine in which the hydroxyl group on carbon 5 of ribose has been replaced with hydrogen. As a result, this compound cannot be phosphorylated and used by DNA polymerase in the synthesis of DNA. 5′-deoxy Thymidine is readily imported by cellular nucleoside importers and competitively inhibits the influx of thymidine.{29379} It demonstrates antibacterial activity against B. subtilis and S. aureus.{29380}

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