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Cyclo(L-Trp-L-Trp)

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    Cyclo(L-Trp-L-Trp)
  • Cyclo(L-Trp-L-Trp)
Cat No: 23494
Biochemicals - Anti-Infection
Cayman

Cyclo(L-Trp-L-Trp) is a cyclic dipeptide that has been used as a substrate for indole prenyltransferases in the synthesis of mono- and diprenylated indolines.{39398,39399} It has antibacterial activity and inhibits growth of 41 out of 49 strains of mu...

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Territorial Availability: Available through Bertin Technologies only in France
Synonyms:
  • 3S,6S-bis(1H-indol-3-ylmethyl)-2,5-piperazinedione
Correlated keywords:
  • 53318-46-0 Acinetobacter Bacillus Micrococcus Staphylococcus Saccharomyces Aspergillus Candida di-prenylated Cyclic L-tryptophanyl-L-tryptophan diketopiperazine dioxopiperazine Cyclo(L-tryptophanyl-L-tryptophan)
Product Overview:
Cyclo(L-Trp-L-Trp) is a cyclic dipeptide that has been used as a substrate for indole prenyltransferases in the synthesis of mono- and diprenylated indolines.{39398,39399} It has antibacterial activity and inhibits growth of 41 out of 49 strains of multidrug resistant A. baumannii (MICs = 12.5-25 µg/ml) as well as B. subtilis, M. luteus, S. aureus, S. cerevisiae, A. niger, and C. albicans (MICs = 12.5-50 µg/ml).{39400} Prenylated forms of cyclo(L-Trp-L-Trp) are cytotoxic against human leukemia and ovarian cell lines.{39401}
Size 50 mg
Shipping dry ice
CAS Number 20829-55-4
Molecular Formula C22H20N4O2
SMILES O=C([C@H](CC1=CNC2=C1C=CC=C2)N3)N[C@@H](CC4=CNC5=C4C=CC=C5)C3=O
Molecular Weight 372,4
Formulation A crystalline solid
Purity ≥98%
Custom Code 2921.30
UNSPSC code 12352100

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Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

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ISO Guide 34:2009

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