1-?-D-Glucosylsphingadienine

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Cat No: 23213

Biochemicals - Lipids

1-β-D-Glucosylsphingadienine is a glucosylsphingosine, which are deacetylated lysolipid derivatives of glucosylcerebrosides (Item Nos. 23206
23207).{41130} They are formed when sphingosines undergo glucosidation by UDP-glucose.{41131} Glucosylsphing...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

2S-amino-3R-hydroxy-4E,8E-octadecadienyl, ?-D-glucopyranoside

Correlated keywords:

52050-17-6 Glucocerebroside Glucopsychosine

Product Overview:
1-β-D-Glucosylsphingadienine is a glucosylsphingosine, which are deacetylated lysolipid derivatives of glucosylcerebrosides (Item Nos. 23206
23207).{41130} They are formed when sphingosines undergo glucosidation by UDP-glucose.{41131} Glucosylsphingosines completely reduce neurite outgrowth and induce death of LA-N-2 cells at concentrations of 10 and 50 μM, respectively. They also decrease the activity of glucocerebrosidase in LA-N-2 cells in a dose-dependent manner. Glucosylsphingosine levels are elevated in patients with Gaucher's disease, both in the spleen (in types 1, 2, and 3) and brain (type 2 and 3); thus, glucosylsphingosine has been used as a key biomarker of the disease.{41130,41132} This product contains 1-β-D-glucosylsphingadienine isolated from plants. [Matreya, LLC. Catalog No. 1310]

Size	500 µg
Shipping	dry ice
CAS Number	114200-59-8
Molecular Formula	C₂₄H₄₅NO₇
SMILES	O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC[C@@H]([C@H](O)/C=C/CC/C=C/CCCCCCCCC)N
Molecular Weight	459,6
Formulation	A solid
Purity	≥98%
Custom Code	2924.19
UNSPSC code	12352100

Technical File

MSDS

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Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

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