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Glucosylceramide (Gaucher’s spleen)

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    Glucosyl<wbr/>ceramide (Gaucher’s spleen)
  • Glucosyl<wbr/>ceramide (Gaucher’s spleen)
Cat No: 23207
Biochemicals - Lipids
Cayman

Glucosylceramides are formed by the tethering of glucose to a ceramide by glucosylceramide synthase.{41133} They are present in neuronal and non-neuronal mammalian tissues and are found at low quantities in a large number of plant species, where they ...

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Territorial Availability: Available through Bertin Technologies only in France
Synonyms:
  • 1-O-?-D-glucopyranosyl-ceramide
Correlated keywords:
  • EGS 21 Glc Gluco-cerebroside HLC SJC Glucopyranosylceramide HLC1 HLC2 HLC3 SJC1 SJC2 SJC3 SJC4 SJC5 EGS21
Product Overview:
Glucosylceramides are formed by the tethering of glucose to a ceramide by glucosylceramide synthase.{41133} They are present in neuronal and non-neuronal mammalian tissues and are found at low quantities in a large number of plant species, where they comprise 5-30% of total lipids in the plant plasma membrane, and in fungi.{41133,41134,59454} Glucosylceramide levels decrease during cold acclimatization in plants and glucosylceramides in fungi are involved in the regulation of virulence and act as elicitors in plants, stimulating plant defense mechanisms.{59454,59455} Glucosylceramides are precursors in the synthesis of lactosylceramides and gangliosides. Increased levels of glucosylceramides are associated with obesity-induced insulin resistance in mice and with neuronal deficits observed in neuronopathic Gaucher disease.{41133,41135} This product is a mixture of glucosylceramides, with variable ceramide chain lengths, isolated from the spleen of a human with Gaucher's disease. [Matreya, LLC. Catalog No. 1057]
Size 1 mg
Shipping dry ice
CAS Number 85305-87-9
Molecular Formula C48H93NO8 (for lignoceryl)
SMILES O[C@H]1[C@H](O)[C@@H](CO)O[C@@H](OC[C@@H]([C@H](O)/C=C/CCCCCCCCCCCCC)NC([R])=O)[C@@H]1O
Molecular Weight 812,3
Formulation A solid
Purity ≥98%
Custom Code 2924.19
UNSPSC code 12352100

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Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

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