?-Estradiol 17-valerate

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Cat No: 22221

Biochemicals - Lipids

β-Estradiol 17-valerate is a synthetic estrogen.{58709,58710,58711} It increases estrogen receptor β (ERβ), but not ERα, levels in the hippocampus and cortex of ovariectomized rats when administered at a dose of 0.3 mg/day.{58709} Intradermal administ...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

(17?)-estra-1,3,5(10)-triene-3,17-diol, 17-pentanoate

Correlated keywords:

907-12-0 69557-95-5 atladiol climaval deladiol delahormone unimatic delestrogen 4x dura-estradiol estraval femogex gynogen LA 40 gynokadin meriestra NSC17590 neofollin nuvelle pelanin pharlon primofol primogyn progynon-depot progynova valergen valerinate valerianate oestradiol 17b ER ? ? hippo campus intra dermal waste water

Product Overview:
β-Estradiol 17-valerate is a synthetic estrogen.{58709,58710,58711} It increases estrogen receptor β (ERβ), but not ERα, levels in the hippocampus and cortex of ovariectomized rats when administered at a dose of 0.3 mg/day.{58709} Intradermal administration of β-estradiol 17-valerate (5 µg/animal) induces transient permanent diestrus and decreases litter size in rats.{58710} β-Estradiol 17-valerate has been used to induce polycystic ovarian syndrome in rats.{58711} It has been found in wastewater effluent.{58712} Formulations containing β-estradiol 17-valerate have been used in hormone replacement therapy and in the treatment of menopausal symptoms, as well as in oral contraceptives in combination with dienogest.

Size	500 mg
Shipping	dry ice
CAS Number	979-32-8
Molecular Formula	C₂₃H₃₂O₃
SMILES	C[C@@]12[C@](CC[C@@H]2OC(CCCC)=O)([H])[C@]([C@]3([H])CC1)([H])CCC4=C3C=CC(O)=C4
Molecular Weight	356,5
Formulation	A crystalline solid
Purity	≥98%
Custom Code	2937.29
UNSPSC code	12352100

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.